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Dublin Core
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Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
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<a href="http://doi.org/10.1002/mds.22660" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/mds.22660</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Comparison of three clinical rating scales in Friedreich ataxia (FRDA)
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Movement Disorders
Date
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2009
Subject
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tone and motor problems; Friedreich's ataxia; trajectory; characteristics; ataxia
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Bürk K; Mälzig U; Wolf S; Heck S; Dimitriadis K; Schmitz-Hübsch T; Hering S; Lindig T M; Haug V; Timmann D; Degen I; Kruse B; Dörr J M; Ratzka S; Ivo A; Schols L; Boesch S; Klockgether T; Klopstock T; Schulz J B
Description
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To test the validity and reliability of the scale for the assessment and rating of ataxia (SARA) in Friedreich ataxia (FRDA). SARA is limited to eight items and can be performed rapidly. Ninety-six patients with a molecular genetic diagnosis of FRDA were rated using three different clinical scales, the FRDA Rating Scale (FARS), the International Cooperative Ataxia Rating Scale (ICARS), and SARA. Despite considerable discrepancies in scale size and subscale structure, SARA total scores were significantly correlated with ICARS (r = 0.953, P < 0.0001) and FARS (r = 0.938, P < 0.0001) total scores. SARA total scores also correlated with the activities of daily living (ADL, r = 0.929, P < 0.0001). Although originally developed for the use in dominantly inherited ataxias, which are primarily ataxias of the cerebellar type, SARA can also be used successfully to assess afferent ataxia, which is the predominant form in FRDA. Because SARA is characterized by high interrater reliability and practicability, SARA is applicable and well suited forclinical trials of FRDA.
Identifier
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<a href="http://doi.org/10.1002/mds.22660" target="_blank" rel="noreferrer noopener">10.1002/mds.22660</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2009
ataxia
Boesch S
Bürk K
characteristics
Degen I
Dimitriadis K
Dörr J M
Friedreich's ataxia
Haug V
Heck S
Hering S
Ivo A
Klockgether T
Klopstock T
Kruse B
Lindig T M
Mälzig U
Movement Disorders
Ratzka S
Schmitz-Hübsch T
Schols L
Schulz J B
Timmann D
tone and motor problems
Trajectory
Wolf S