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Dublin Core
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Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
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<a href="http://doi.org/10.1002/ana.410060312" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/ana.410060312</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Disturbances of Rapid-Eye-Movement Sleep in 3 Brothers with Pelizaeus-Merzbacher Disease
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Annals of Neurology
Date
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1979
Subject
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Neurosciences & Neurology; sleep disturbance/disorders; Pelizaeus-Merzbacher disease; trajectory; characteristics; REM sleep
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Niakan E; Belluomini J; Lemmi H; Summitt R L; Chien L
Description
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The electrophysiological features of 3 brothers with the classic form of Pelizaeus-Merzbacher disease (PMD) were studied. Two consecutive overnight polygraphic sleep recordings indicated a gross distortion of rapid-eye-movement (REM) sleep for all patients. A lower than normal percentage of REM sleep in these patients was consistent with their retarded intellectual development, which supports current thinking that REM sleep may be a sensitive index of brain function integrity. Non-rapid-eye-movement (NREM) sleep, in contrast to reported findings in 1 patient with PMD, was uniformly characterized by distinct stages in which the electroencephalograms contained frequent vertex waves and spindles. Tests of peripheral nerve conduction velocity, acoustic brainstem reflexes, and visual and auditory evoked potentials did not indicate any abnormalities, nor did electroencephalograms obtained during wakefulness. One patient did have epileptiform spikes and spike waves recorded during an all-night EEG, an unusual finding in a child with cerebral white matter disease.
Identifier
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<a href="http://doi.org/10.1002/ana.410060312" target="_blank" rel="noreferrer noopener">10.1002/ana.410060312</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
1979
Annals Of Neurology
Belluomini J
characteristics
Chien L
Lemmi H
Neurosciences & Neurology
Niakan E
Pelizaeus-Merzbacher disease
REM sleep
sleep disturbance/disorders
Summitt R L
Trajectory