1
40
3
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
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URL Address
<a href="http://doi.org/10.1001/jama.296.13.1602" target="_blank" rel="noreferrer">http://doi.org/10.1001/jama.296.13.1602</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Clinical and MRI correlates of cerebral palsy: the European Cerebral Palsy Study
Publisher
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Jama
Date
A point or period of time associated with an event in the lifecycle of the resource
2006
Subject
The topic of the resource
Child; Cross-Sectional Studies; Female; Humans; infant; Male; Pregnancy; Pregnancy Complications; Risk Factors; Magnetic Resonance Imaging; Preschool; infant; Newborn; Premature; Brain/pathology; Cerebral Palsy/epidemiology/etiology/physiopathology; Delivery; Infectious; Multiple; Obstetric
Creator
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Bax M; Tydeman C; Flodmark O
Description
An account of the resource
CONTEXT: Magnetic resonance imaging (MRI) findings have been reported for specific clinical cerebral palsy (CP) subgroups or lesion types but not in a large population of children with all CP subtypes. Further information about the causes of CP could help identify preventive strategies. OBJECTIVE: To investigate the correlates of CP in a population sample and compare clinical findings with information available from MRI brain studies. DESIGN AND SETTING: Cross-sectional, population-based investigative study conducted in 8 European study centers (North West London and North East London, England; Edinburgh, Scotland; Lisbon, Portugal; Dublin, Ireland; Stockholm, Sweden; Tubingen, Germany; and Helsinki, Finland). PARTICIPANTS: Five hundred eighty-five children with CP were identified who had been born between 1996 and 1999; 431 children were clinically assessed and 351 had a brain MRI scan. MAIN OUTCOME MEASURES: Standardized clinical examination results, parental questionnaire responses, MRI results, and obstetric, genetic, and metabolic data from medical records. RESULTS: Important findings include the high rate of infections reported by mothers during pregnancy (n = 158 [39.5%]). In addition, 235 children (54%) were born at term while 47 children (10.9%) were very preterm (<28 weeks). A high rate of twins was found, with 51 children (12%) known to be from a multiple pregnancy. Clinically, 26.2% of children had hemiplegia, 34.4% had diplegia, 18.6% had quadriplegia, 14.4% had dyskinesia, 3.9% had ataxia, and 2.6% had other types of CP. Brain MRI scans showed that white-matter damage of immaturity, including periventricular leukomalacia (PVL), was the most common finding (42.5%), followed by basal ganglia lesions (12.8%), cortical/subcortical lesions (9.4%), malformations (9.1%), focal infarcts (7.4%), and miscellaneous lesions (7.1%). Only 11.7% of these children had normal MRI findings. There were good correlations between the MRI and clinical findings. CONCLUSIONS: These MRI findings suggest that obstetric mishaps might have occurred in a small proportion of children with CP. A systematic approach to identifying and treating maternal infections needs to be developed. Multiple pregnancies should be monitored closely, and the causes of infant stroke need to be investigated further so preventive strategies can be formulated. All children with CP should have an MRI scan to provide information on the timing and extent of the lesion.
2006
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1001/jama.296.13.1602" target="_blank" rel="noreferrer">10.1001/jama.296.13.1602</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2006
Backlog
Bax M
Brain/pathology
Cerebral Palsy/epidemiology/etiology/physiopathology
Child
Cross-sectional Studies
Delivery
Female
Flodmark O
Humans
Infant
Infectious
JAMA
Journal Article
Magnetic Resonance Imaging
Male
Multiple
Newborn
Obstetric
Pregnancy
Pregnancy Complications
Premature
Preschool
Risk Factors
Tydeman C
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1111/j.1469-8749.1964.tb10791.x" target="_blank" rel="noreferrer">http://doi.org/10.1111/j.1469-8749.1964.tb10791.x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Terminology and classification of cerebral palsy
Publisher
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Developmental Medicine & Child Neurology
Date
A point or period of time associated with an event in the lifecycle of the resource
1964
Subject
The topic of the resource
Child; Cerebral Palsy; Terminology; Classification
Creator
An entity primarily responsible for making the resource
Bax M
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1469-8749.1964.tb10791.x" target="_blank" rel="noreferrer">10.1111/j.1469-8749.1964.tb10791.x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
1964
1964
Backlog
Bax M
Cerebral Palsy
Child
Classification
Developmental Medicine & Child Neurology
Journal Article
Terminology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
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URL Address
<a href="http://doi.org/10.1111/j.1469-8749.1996.tb12114.x" target="_blank" rel="noreferrer">http://doi.org/10.1111/j.1469-8749.1996.tb12114.x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Sleep problems in children with Sanfilippo syndrome.
Publisher
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Developmental Medicine And Child Neurology
Date
A point or period of time associated with an event in the lifecycle of the resource
1996
Subject
The topic of the resource
Child; Female; Humans; Male; Questionnaires; Longitudinal Studies; Time Factors; Preschool; Sleep Disorders/etiology; Sleep Disorders/therapy; Mucopolysaccharidosis III/classification; Mucopolysaccharidosis III/complications
Creator
An entity primarily responsible for making the resource
Colville GA; Watters JP; Yule W; Bax M
Description
An account of the resource
Sanfilippo syndrome is a rare degenerative disorder which has severe intellectual and behavioural sequelae, commonly including sleep problems. A parental questionnaire was used to gather information on the sleep patterns of 80 children with Sanfilippo syndrome (mean age 10 years 2 months). The majority were found to have sleep problems (78%). Many also exhibited other distressing and unusual night time behaviours (staying up all night, chewing the bedclothes or crying out suddenly), and a few laughed or sang. Such problems may have been more severe in those with Sanfilippo syndrome type B. In four of the families offered individually tailored behaviour-management advice there was immediate improvement, which was maintained at followup in two cases. These results demonstrate the usefulness of even such a minimal intervention, even in a very difficult population such as this.
1996
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1469-8749.1996.tb12114.x" target="_blank" rel="noreferrer">10.1111/j.1469-8749.1996.tb12114.x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1996
Backlog
Bax M
Child
Colville GA
Developmental Medicine and Child Neurology
Female
Humans
Journal Article
Longitudinal Studies
Male
Mucopolysaccharidosis III/classification
Mucopolysaccharidosis III/complications
Preschool
Questionnaires
Sleep Disorders/etiology
Sleep Disorders/therapy
Time Factors
Watters JP
Yule W