Browse Items · Pediatric Palliative Care Library

A possible role for saliva as a diagnostic fluid in patients with chronic pain

OBJECTIVES: The focus of this review was on proteins and peptides found in saliva. Of greatest interest were those neuropeptides relevant to nociception and to the pathogenesis of chronic pain syndromes. An additional goal was to develop a…

Assessing the clinical importance of symptomatic improvements. An illustration in rheumatology

OBJECTIVE: To estimate when a difference in disability symptoms is sufficiently large to be important to individual patients. DESIGN: Cross-sectional analysis of two groups: derivation set (n = 46) and validation set (n = 57). SETTING: The Arthritis…

Beta-endorphin, Met-enkephalin and corresponding opioid receptors within synovium of patients with joint trauma, osteoarthritis and rheumatoid arthritis

OBJECTIVE: Intra-articularly applied opioid agonists or antagonists modulate pain after knee surgery and in chronic arthritis. Therefore, the expression of beta-endorphin (END), Met-enkephalin (ENK), and mu and delta opioid receptors (ORs) within…

Depression and anxiety in rheumatoid arthritis: the role of perceived social support

BACKGROUND: Rheumatoid arthritis is a common, disabling, autoimmune disease with significant psychiatric sequelae. AIMS: We aimed to identify the prevalence of depression and anxiety in patients with rheumatoid arthritis attending hospitals, and to…

Development and pilot-testing of a health-related quality of life chronic generic module for children and adolescents with chronic health conditions: a European perspective

2005

Tags: 'Independence', 'Physical', 'Social Exclusion') with acceptable internal consistency., 'Social Inclusion', 13-16 years) with different chronic health conditions (asthma, 2005, Adolescent Child Chronic Disease/psychology Disabled Children/psychology Europe Health Status Humans Pilot Projects Quality of Life/psychologyQuestionnaires Research Support, and cystic fibrosis) as well as their families were included. Data were analysed according to predefined psychometric and content criteria. Psychometric an alyses resulted in a 56-item chronic generic HRQOL questionnaire with six domains ('Medication', and implement European instruments for the assessment of HRQOL of children and adolescents with disabilities and their families. The current paper describes the development and pilot testing of a chronic generic HRQOL measure. Using literature searches, Arthritis, atopic dermatitis, Backlog, Bullinger M, Cerebral Palsy, Diabetes, Emotion, Epilepsy, expert consulting and focus groups with children/adolescents and their families, items of the instruments were developed and translated into the respective languages. A pilot test with 360 children and adolescents was conducted. Children and adolescents (8-12, Journal Article, Non-U.S. Gov'tSickness Impact Profile%X Health-related quality of life (HRQOL) assessment in children and adolescents with chronic health conditions is increasingly considered as a relevant topic. The aim of the EU-funded DISABKIDS project is to develop, PedPal Lit, Petersen C, Power M, Quality of Life Research, Schmidt S, test

Development and preliminary validation of the 'Mind the Gap' scale to assess satisfaction with transitional health care among adolescents with juvenile idiopathic arthritis

BACKGROUND: To develop a scale to assess satisfaction with transitional health care among adolescents with a chronic illness and their parents. METHODS: The 'Mind the Gap' scale was developed using evidence from a previous needs assessment, in three…

Functional ability, social support, and depression in rheumatoid arthritis

OBJECTIVE: First, to investigate the patterns of functional ability, depressive feelings, and social support in early stage rheumatoid arthritis (RA) patients. Second, to demonstrate the stress buffering effect of social support. Social support is…

Individual differences, mood, and coping with chronic pain in Rheumatoid Arthritis: a daily process analysis.

This study examines individual differences in coping and associated health outcomes as they unfold across time. Twice daily for one week, 71 individuals with Rheumatoid Arthritis reported their pain, coping efforts, and negative mood via structured…

Tags: 2004, Adaptation, Arthritis, Backlog, Chronic Pain, Coping, Coping Behavior, Coping Skills, DeLongis A, Journal Article, Mood, Newth S, Pain, Psychological, Psychology & Health, Rheumatoid, Rheumatoid Arthritis

Late consequences of chronic pediatric illness

There are many challenges in coping with and adapting to life with a chronic disease, and increased survival cannot be assumed to be associated with increased quality of life. A recent systematic review shows there is wide variation in outcomes…

Tags: 2007, Adolescent, Arthritis, Backlog, Child, Chronic Disease/psychology, Congenital/diagnosis/epidemiology/psychology, Cystic Fibrosis/diagnosis/epidemiology/psychology, Diagnosis, Differential, Heart Defects, Humans, Journal Article, Juvenile Rheumatoid/diagnosis/epidemiology/psychology, Mental Disorders/diagnosis/epidemiology/etiology, Pao M, The Psychiatric Clinics Of North America, Time Factors, Turkel S

Opioid peptides endomorphin-1 and endomorphin-2 in the immune system in humans and in a rodent model of inflammation

Endomorphin (EM)-1 and EM-2 are tetrapeptides with high affinity and selectivity for the micro-opioid receptor. We have utilized specific radioimmunoassays to characterize EM-1 and EM-2 in immune tissues from normal human subjects and from rats with…

Perceived importance of activities of daily living and arthritis helplessness in rheumatoid arthritis

OBJECTIVE: To examine the contribution of perceived importance of activities of daily living (ADL) to arthritis-specific helplessness in a sample of rheumatoid arthritis (RA) patients over a 1-year period. METHOD: Forty-two individuals from an…

Rheumatoid cachexia: metabolic abnormalities, mechanisms and interventions

We have previously identified the phrase 'rheumatoid cachexia' to describe the loss of body cell mass (BCM) that may occur among patients with rheumatoid arthritis (RA). Specifically, rheumatoid cachexia is characterized by altered energy and protein…

Tags: 2004, Aging/physiology, Arthritis, Backlog, Cachexia/complications/metabolism/therapy, Cytokines/antagonists & inhibitors/metabolism, Diet, Energy Metabolism/physiology, Exercise Therapy, Hormones/metabolism, Humans, Intervention, Interventions, Journal Article, Proteins/metabolism, Rall LC, Rheumatoid/complications/metabolism/therapy, Rheumatology, Roubenoff R

Support as a crucial predictor of good compliance of adolescents with a chronic disease

The purpose of this study was to describe the factors that predict compliance among adolescents with a chronic illness. The data were collected by questionnaires from adolescents with asthma, epilepsy, juvenile rheumatoid arthritis (JRA) and…

The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis

OBJECTIVE: To assess and compare the impact of medication treatments on health-related quality of life (HRQOL), family function, and medical status in children with juvenile idiopathic arthritis (JIA). METHODS: Fifty-seven children diagnosed with JIA…

The interaction of physical function and emotional well-being in rheumatoid arthritis--what is the impact on disease activity and coping?

OBJECTIVE: To evaluate the impact of the interaction of physical function and emotional well-being on disease-related parameters and coping with rheumatoid arthritis. METHODS: A cross-sectional survey among 177 RA patients included demographic and…

The Role of Social Support in Coping with Daily Pain among Patients with Rheumatoid Arthritis

Using a daily process methodology, the current study examined the role of social support in coping and pain severity among patients with rheumatoid arthritis (RA). Seventy-three adults with RA completed a structured record twice daily for one week on…

The role of the central nervous system in the generation and maintenance of chronic pain in rheumatoid arthritis, osteoarthritis and fibromyalgia

Pain is a key component of most rheumatologic diseases. In fibromyalgia, the importance of central nervous system pain mechanisms (for example, loss of descending analgesic activity and central sensitization) is well documented. A few studies have…

Tags: 2011, Animals, Arthritis, Arthritis Research & Therapy, Backlog, Central Nervous System/physiopathology, Chronic Pain/complications/physiopathology, Clauw DJ, Fibromyalgia/complications/physiopathology, Humans, Journal Article, Lee YC, Nassikas NJ, Osteoarthritis/complications/physiopathology, Rheumatoid/complications/physiopathology

Young people's satisfaction of transitional care in adolescent rheumatology in the UK

BACKGROUND: To examine the quality of transitional health care from the perspectives of young people with juvenile idiopathic arthritis (JIA) and their parents. METHODS: Adolescents with JIA and their parents were recruited from 10 major UK…

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