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Dublin Core
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Title
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Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
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URL Address
<a href="http://doi.org/10.1136/adc.69.2.191" target="_blank" rel="noreferrer noopener">http://doi.org/10.1136/adc.69.2.191</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Breathing abnormalities in sleep in achondroplasia
Publisher
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Archives in Disease in Childhood
Date
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1993
Subject
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breathing difficulties; achondroplasia; trajectory; characteristics; upper airways obstruction
Creator
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Waters K A; Everett F; Sillence D; Fagan E; Sullivan C E
Description
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Overnight sleep studies were performed in 20 subjects with achondroplasia to document further the respiratory abnormalities present in this group. Somatosensory evoked potentials (SEPs) were recorded in 19 of the subjects to screen for the presence of brainstem abnormalities, which are one of the potential aetiological mechanisms. Fifteen children aged 1 to 14 years, and five young adults, aged 20 to 31 years were included. All had upper airway obstruction and 15 (75%) had a pathological apnoea index (greater than five per hour). Other sleep associated respiratory abnormalities, including partial obstruction, central apnoea, and abnormal electromyographic activity of accessory muscles of respiration, also showed a high prevalence. SEPs were abnormal in eight (42%), but there was no correlation between abnormal SEPs and apnoea during sleep, either qualitatively or quantitatively. A high prevalence of both sleep related respiratory abnormalities and abnormal SEPs in young subjects with achondroplasia was demonstrated. However, the sleep related respiratory abnormalities do not always result in significant blood gas disturbances or correlate with abnormal SEPs in this group.
Identifier
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<a href="http://doi.org/10.1136/adc.69.2.191" target="_blank" rel="noreferrer noopener">10.1136/adc.69.2.191</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
1993
achondroplasia
Archives in Disease in Childhood
breathing difficulties
characteristics
Everett F
Fagan E
Sillence D
Sullivan C E
Trajectory
upper airways obstruction
Waters K A