Risperidone in children with autism and serious behavioral problems
Humans; Adult; adolescent; Antipsychotic Agents/adverse effects; Autistic Disorder/drug therapy; Risperidone/adverse effects; Hyperprolactinemia/chemically induced; Hypogonadism/chemically induced; Osteoporosis/chemically induced
2002
Valiquette G
The New England Journal Of Medicine
2002
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Journal Article
<a href="http://doi.org/10.1056/nejmoa013171" target="_blank" rel="noreferrer">10.1056/nejmoa013171</a>
Risperidone in children with autism and serious behavioral problems
Child; Humans; Male; Antipsychotic Agents/adverse effects; Autistic Disorder/drug therapy; Bipolar Disorder/drug therapy; Priapism/chemically induced; Psychotic Disorders/drug therapy; Risperidone/adverse effects
2002
Munarriz R; Bennett L; Goldstein I
The New England Journal Of Medicine
2002
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Journal Article
<a href="http://doi.org/10.1056/nejmoa013171" target="_blank" rel="noreferrer">10.1056/nejmoa013171</a>
Measurement of the validity of utility elicitations performed by computerized interview
Humans; Adult; Aged; Middle Aged; Choice Behavior; Patient Satisfaction; Reproducibility of Results; adolescent; Non-U.S. Gov't; P.H.S.; Research Support; U.S. Gov't; Nonparametric; Statistics; Akathisia; Drug-Induced/etiology; Antipsychotic Agents/adverse effects; Dyskinesia; Interviews/standards; Multimedia/standards; Parkinson Disease; Schizophrenia/drug therapy; Schizophrenic Psychology; Secondary/chemically induced
OBJECTIVES: The authors evaluate a measure of the validity of utility elicitations and study the potential effects of invalid elicitations on population utility values. METHODS: The authors used a computerized survey to describe and measure preferences for three common side-effects of anti-psychotic drugs (tardive dyskinesia [TD], akathesia [AKA], pseudo-parkinsonism). The authors compared the validity of elicitations in 41 healthy volunteers to 22 schizophrenic patients. Preferences were measured using visual analog scale (VAS), pair-wise comparison (PWC), and the Standard Gamble (SG) methods. To assess the validity of each groups' responses, the authors compared the consistency of subjects' rank-order of the desirability of states across methods of preferences assessment (CAMPA). RESULTS: All healthy volunteers and 82% of patients completed the computer survey; of these subjects, 97% of healthy volunteers and 70% of patients indicated they thought they understood the task required of them. However, only 78% of healthy subjects and 44% of patients had a consistent rank ordering of preferences among VAS and PWC ratings; only 80% and 61%, respectively, had a consistent rank ordering preferences among SG and PWC ratings. For two of the three health states, inconsistent subjects had statistically higher SG utilities (for TD, 0.94 versus 0.87, and for AKA 0.92 versus 0.86; P < 0.05). CONCLUSIONS: The CAMPA test can identify potentially invalid preference ratings. Potentially invalid preference ratings may bias the "population" utilities for health states.
1997
Lenert LA; Morss S; Goldstein MK; Bergen MR; Faustman WO; Garber AM
Medical Care
1997
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Journal Article
<a href="http://doi.org/10.1097/00005650-199709000-00004" target="_blank" rel="noreferrer">10.1097/00005650-199709000-00004</a>