Browse Items · Pediatric Palliative Care Library

New antidepressive and antipsychotic drugs in juvenile neuronal ceroid lipofuscinoses--a pilot study

Patients with juvenile neuronal ceroid lipofuscinosis (JNCL) often have severe psychiatric symptoms. These are common in their mid-teens and include such symptoms as anxiety and affective and psychotic disorders. The older antidepressants and…

T-lymphocyte concentrations of cholecystokinin-8 and beta-endorphin in eating disorders: II. Bulimia nervosa

Concentrations of cholecystokinin-8 (CCK-8) and beta-endorphin (beta-EP) in T-lymphocytes of 26 women with bulimia nervosa (BN) and in 26 age- and sex-matched healthy comparison subjects were measured. Ten patients were then treated with 300 mg/day…

Pain and symptom control in terminally ill children

The management of pain in terminally ill pediatric patients has incalculable benefits to patients, their families, and physicians and nurses. A therapeutic management plan is dependent on a thorough understanding of the causes of pain in these…

Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy

BACKGROUND: Functional imaging studies of major depressive disorder demonstrate response-specific regional changes following various modes of antidepressant treatment. OBJECTIVE: To examine changes associated with cognitive behavior therapy (CBT).…

Tags: 2004, Adult, Ambulatory Care, Antidepressive Agents, Archives Of General Psychiatry, Backlog, Bieling P, Blood Glucose/metabolism, Brain Mapping, Cerebral Cortex/physiopathology/radionuclide imaging, Cognitive Therapy, Comparative Study, Depressive Disorder, Emission-Computed, Energy Metabolism/physiology, Female, Fluorodeoxyglucose F18/diagnostic use, Follow-up Studies, Frontal Lobe/physiopathology/radionuclide imaging, Garson C, Goldapple K, Humans, Journal Article, Kennedy S, Lau M, Limbic System/physiopathology/radionuclide imaging, Major/physiopathology/radionuclide imaging/therapy, Male, Mayberg H, Middle Aged, Nerve Net/physiopathology/radionuclide imaging, Neural Pathways/physiopathology/radionuclide imaging, Non-U.S. Gov't, Outcome And Process Assessment (health Care), Paroxetine/therapeutic use, Personality Inventory, Prefrontal Cortex/physiopathology/radionuclide imaging, Research Support, Second-Generation/therapeutic use, Segal Z, Sensitivity and Specificity, Tomography

Focus on paroxetine

This review of paroxetine is based on Medline and PsycLit searches and a manual search of the available research literature. It aims to cover the pharmacology of this frequently prescribed SSRI antidepressant in terms of its indications, efficacy and…

Tags: 2003, Animals, Antidepressive Agents, Anxiety Disorders/drug therapy, Backlog, Current Medical Research And Opinion, Depression/drug therapy, Drug Interactions, Green B, Humans, Journal Article, Paroxetine/administration & dosage/adverse effects/pharmacokinetics/therapeutic use, Post-Traumatic/drug therapy, Second-Generation/administration & dosage/adverse effects/pharmacokinetics/therapeutic use, Serotonin Uptake Inhibitors/administration & dosage/adverse effects/pharmacokinetics/therapeutic use, Stress Disorders, Substance Withdrawal Syndrome, Treatment Outcome

Antidepressant comparison chart

Efficacy of pharmacological treatments of neuropathic pain: An update and effect related to mechanism of drug action

Tricyclic antidepressants and carbamazepine have become the mainstay in the treatment of neuropathic pain. Within the last decade, controlled trials have shown that numerous other drugs relieve such pain. We identified all placebo-controlled trials…

Combining single patient (N-of-1) trials to estimate population treatment effects and to evaluate individual patient responses to treatment

When treating individual patients, physicians may face difficulties using the evidence from center-based randomized control trials (RCTs) due to limitations in these studies generalizability. Therefore, they often perform their own "informal" tests…

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