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Text
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URL Address
<a href="http://doi.org/10.1097/00003465-200411000-00001" target="_blank" rel="noreferrer">http://doi.org/10.1097/00003465-200411000-00001</a>
Dublin Core
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Title
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The biochemical basis of metabolism in cancer cachexia
Publisher
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Dimensions Of Critical Care Nursing
Date
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2004
Subject
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Humans; Survival Rate; Disease Progression; Neoplasms/complications; Energy Metabolism; Nutritional Failure; Antineoplastic Agents/therapeutic use; Lipid Metabolism; Carbohydrate Metabolism; Proteins/metabolism; Anorexia/etiology; Appetite Stimulants/therapeutic use; Cachexia/etiology/metabolism/mortality/physiopathology/therapy; Cytokines/antagonists & inhibitors/physiology; Hydrazines/therapeutic use; Nutritional Support/methods; Weight Loss
Creator
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Tijerina AJ
Description
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Cancer cachexia is a syndrome of progressive body wasting characterized by loss of adipose tissue and skeletal muscle mass. It is the most common side effect of malignancy occurring in approximately one-half of untreated cancer patients. The pathophysiology of cancer cachexia is not fully understood; however, studies have shown that cytokines are important in the alteration of carbohydrate, lipid, and protein metabolism. This leads to a shorter survival time and a decreased response to therapy. Cachexia is often found before any signs or symptoms of the cancer. An uncertainty with cachexia is whether nutritional support is feeding the patient or the tumor. Often, cachexia is not responsive to simple nutritional interventions. Furthermore, appetite stimulants, cytokine inhibitors, and Cori cycle inhibitors have been used to treat cancer cachexia.
2004
Identifier
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<a href="http://doi.org/10.1097/00003465-200411000-00001" target="_blank" rel="noreferrer">10.1097/00003465-200411000-00001</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
2004
Anorexia/etiology
Antineoplastic Agents/therapeutic use
Appetite Stimulants/therapeutic use
Backlog
Cachexia/etiology/metabolism/mortality/physiopathology/therapy
Carbohydrate Metabolism
Cytokines/antagonists & inhibitors/physiology
Dimensions Of Critical Care Nursing
Disease Progression
Energy Metabolism
Humans
Hydrazines/therapeutic use
Journal Article
Lipid Metabolism
Neoplasms/complications
Nutritional Failure
Nutritional Support/methods
Proteins/metabolism
Survival Rate
Tijerina AJ
Weight Loss