Browse Items (95 total)
- Tags: Animals
Modulation of peripheral endogenous opioid analgesia by central afferent blockade
Tags: 2003, Afferent/drug effects, Analgesics, Anesthesiology, Animals, Backlog, beta-Endorphin/metabolism, Brack A, Central Nervous System/drug effects, Endorphins/metabolism/physiology, Enkephalin, Flow Cytometry, Foot/pathology, Immunohistochemistry, Inflammation/pathology, Injections, Journal Article, Male, Methionine/metabolism, Morphine/administration & dosage/pharmacology, Mousa SA, Neurons, Opioid/administration & dosage/pharmacology, Pain Threshold/drug effects, Peripheral Nerves/drug effects, Psychomotor Performance/drug effects, Rats, Rittner HL, Schafer M, Schmidt DK, Schmitt TK, Spinal, Stein C, Welte M, Wistar
Mobilization of opioid-containing polymorphonuclear cells by hematopoietic growth factors and influence on inflammatory pain
Tags: 2004, Anesthesiology, Animals, Backlog, Beschmann K, Biomarkers of Pain, Brack A, Cell Adhesion Molecules/pharmacology, Cell Separation, Chemokines/biosynthesis, Chemotaxis, DNA Primers, Flow Cytometry, Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology, Hindlimb/physiology, Inflammation/complications, Journal Article, Leukocyte/drug effects, Light, Machelska H, Male, Messenger/biosynthesis, Narcotics/metabolism/pharmacology, Neutrophils/metabolism, Pain Measurement/drug effects, Pain/drug therapy/physiopathology, Radioimmunoassay, Rats, Reverse Transcriptase Polymerase Chain Reaction, Rittner HL, RNA, Schafer M, Sitte N, Stein C, Stem Cell Factor/pharmacology, Wistar
Tissue monocytes/macrophages in inflammation: hyperalgesia versus opioid-mediated peripheral antinociception
Tags: 2004, Analgesics, Anesthesiology, Animals, Backlog, Biomarkers of Pain, Brack A, Clodronic Acid/pharmacokinetics/pharmacology, Fentanyl/administration & dosage/pharmacology, Flow Cytometry, Foot/pathology, Freund's Adjuvant, Heat, Hyperalgesia/chemically induced/pathology/psychology, Inflammation/chemically induced/pathology, Injections, Journal Article, Labuz D, Liposomes, Machelska H, Macrophages/pathology, Male, Monocytes/pathology, Non-Narcotic/pharmacokinetics/pharmacology, Opioid/administration & dosage/pharmacology, Pain Measurement/drug effects, Pressure, Rats, Reszka R, Rittner HL, Schafer M, Schiltz A, Stein C, Wistar
Opioid peptides endomorphin-1 and endomorphin-2 in the immune system in humans and in a rodent model of inflammation
Tags: 2002, Animals, Annals Of The New York Academy Of Sciences, Apoptosis/drug effects, Arthritis, Backlog, Concanavalin A/pharmacology, Experimental/immunology/metabolism, Harbuz MS, Humans, Jessop DS, Journal Article, Lipopolysaccharides/pharmacology, Lymphocyte Activation/drug effects, Lymphocyte Subsets/chemistry/drug effects, Male, Morphine/pharmacology, Non-U.S. Gov't, Oligopeptides/analysis/pharmacology, Radioimmunoassay, Rats, Research Support, Richards LJ, Spleen/chemistry, Synovial Fluid/chemistry, Thymus Gland/chemistry, Wistar
Hypothalamo-pituitary-adrenal axis and chronic immune activation
Tags: 2003, Animal, Animals, Annals Of The New York Academy Of Sciences, Autoimmune Diseases/immunology/physiopathology, Backlog, Chover-Gonzalez AJ, Corticosterone/secretion, Disease Models, Harbuz MS, Humans, Hypothalamo-Hypophyseal System/physiopathology, Immune System Diseases/physiopathology, Inflammation/immunology/physiopathology, Jessop DS, Journal Article, Pituitary-Adrenal System/physiopathology, Stress/immunology
Topical and peripherally acting analgesics
Tags: 2003, Administration, Afferent/drug effects/metabolism/physiology, Analgesics/administration & dosage/pharmacology/therapeutic use, Animals, Backlog, Humans, Journal Article, Neurons, Nociceptors/metabolism/physiology, Non-U.S. Gov't, Pain/drug therapy/metabolism/physiopathology, Peripheral Nervous System/drug effects, Pharmacological Reviews, Research Support, Sawynok J, Signal Transduction/drug effects/physiology, Topical
Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle
Tags: 2003, Adult, Afferent Pathways/drug effects/physiology, Analysis of Variance, Animals, Arendt-Nielsen L, Backlog, Berde CB, Cairns BE, Cross-Over Studies, Dose-Response Relationship, Double-Blind Method, Drug, Female, Glutamic Acid/pharmacology, Graven-Nielsen T, Humans, Hupfeld S, Journal Article, Journal Of Neurophysiology, Male, Masseter Muscle/drug effects/physiology, N-Methyl-D-Aspartate/agonists/antagonists & inhibitors/metabolism, Non-U.S. Gov't, Nonparametric, Pain/chemically induced/physiopathology, Rats, Receptors, Research Support, Sessle BJ, Sprague-Dawley, Statistics, Svensson P, Wang K
Focus on paroxetine
Tags: 2003, Animals, Antidepressive Agents, Anxiety Disorders/drug therapy, Backlog, Current Medical Research And Opinion, Depression/drug therapy, Drug Interactions, Green B, Humans, Journal Article, Paroxetine/administration & dosage/adverse effects/pharmacokinetics/therapeutic use, Post-Traumatic/drug therapy, Second-Generation/administration & dosage/adverse effects/pharmacokinetics/therapeutic use, Serotonin Uptake Inhibitors/administration & dosage/adverse effects/pharmacokinetics/therapeutic use, Stress Disorders, Substance Withdrawal Syndrome, Treatment Outcome
Hormones and the stressed brain
Subcellular pathways of beta-endorphin synthesis, processing, and release from immunocytes in inflammatory pain
Tags: 2004, Animals, Backlog, beta-Endorphin/biosynthesis, Biomarkers of Pain, Carboxypeptidase H/metabolism, Endocrinology, Extremities, Immunoelectron, Immunohistochemistry, Inflammation/immunology/metabolism, Journal Article, Leukocytes/drug effects/metabolism/ultrastructure, Male, Microscopy, Mousa SA, Norepinephrine/pharmacology, Pain/immunology/metabolism, Pro-Opiomelanocortin/metabolism, Proprotein Convertase 1/metabolism, Proprotein Convertase 2/metabolism, Rats, Schafer M, Secretory Vesicles/metabolism/ultrastructure, Shakibaei M, Sitte N, Stein C, Sympathomimetics/pharmacology, Wistar
Immune mechanisms in pain control
Tags: 2002, Analgesics, Anesthesia & Analgesia, Animals, Backlog, Cellular/physiology, Endorphins/metabolism, Humans, Immune System/physiology, Immunity, Journal Article, Machelska H, Non-U.S. Gov't, Opioid/pharmacology, Opioid/physiology, Pain/drug therapy/immunology/pathology, Receptors, Research Support, Stein C
Proopiomelanocortin, a polypeptide precursor with multiple functions: from physiology to pathological conditions
Modern therapy for Paget's disease of bone: focus on bisphosphonates
Diphosphonates: history and mechanisms of action
Tags: 1981, Animals, Backlog, Bone Resorption/drug effects, Calcification, Calcinosis/drug therapy, Calcium Phosphates/metabolism, Clodronate, Clodronic Acid, Diphosphates/pharmacology, Diphosphonates/metabolism/pharmacology/therapeutic use, Etidronic Acid/pharmacology, Fleisch H, Humans, Journal Article, Metabolic Bone Disease & Related Research, Methylene Chloride, Non-U.S. Gov't, Physiologic/drug effects, Polyphosphates/pharmacology, Research Support
Peripheral opioid receptors mediating antinociception in inflammation. Activation by endogenous opioids and role of the pituitary-adrenal axis
Tags: 1990, Adrenalectomy, Analysis of Variance, Animals, Backlog, Biomarkers of Pain, Biomarkers Reference List, Cold, Czlonkowski A, Dose-Response Relationship, Drug, Endorphins/physiology, Foot, Herz A, Hypophysectomy, Inbred Strains, Inflammation/physiopathology, Journal Article, Male, Naloxone/pharmacology, Naltrexone/pharmacology, Nociceptors/physiopathology, Opioid/physiology, Pain, Parsons CG, Pituitary-Adrenal System/physiology, Rats, Receptors, Stein C, Stress/physiopathology, Swimming
Spontaneous pneumothorax, pneumomediastinum, and pneumopericardium in a 16-year-old drug-abusing motorcyclist surrounded by a pack of coyotes
Tags: 1989, Adolescent, Animals, Backlog, Chop WM, Haines JD, Humans, Journal Article, Male, Mediastinal Emphysema/etiology, Motorcycles, Panic, Pneumopericardium/etiology, Pneumothorax/etiology, Postgraduate Medicine, Smoke Inhalation Injury/complications, Substance-Related Disorders/complications, Swyden SN, Wild
beta-Endorphin and adrenocorticotropin are selected concomitantly by the pituitary gland
Tags: 1977, Adrenocorticotropic Hormone/blood/secretion, Amino Acid Sequence, Animals, Backlog, Biomarkers of Pain, Bloom F, Corticotropin-Releasing Hormone/pharmacology, Endorphins/blood/secretion, Guillemin R, Hypophysectomy, Journal Article, Ling N, Male, Minick S, Peptides/secretion, Physiological/blood, Pituitary Gland/secretion, Protein Precursors/secretion, Rats, Rivier C, Rossier J, Science, Stress, Time Factors, Vale W, Vargo T
Fasting associated with decrease in hypothalamic beta-endorphin
Aspects of altered metabolism in children with cancer
Tags: 1998, Animals, Backlog, Cachexia/etiology, Child, Energy Metabolism, Humans, Interleukin-1/physiology, Interleukin-6/physiology, International Journal Of Cancer. Supplement, Journal Article, Neoplasms/complications/metabolism/physiopathology, Nutritional Failure, Nutritional Requirements, Picton SV, Tumor Necrosis Factor-alpha/physiology
Associations between the neuroendocrine and immune systems
Tags: 1995, Animals, Backlog, Biomarkers of Pain, Blalock JE, Cell Communication, Cytokines/physiology, Hormones/physiology, Humans, Hypothalamo-Hypophyseal System/physiology, Immune System/physiology, Interleukins/physiology, Journal Article, Journal Of Leukocyte Biology, Leukocytes/physiology, Neurosecretory Systems/physiology, Signal Transduction, Weigent DA
Intermittent but not continuous inescapable footshock stress affects immune responses and immunocyte beta-endorphin concentrations in the rat
Tags: 1994, Acute Disease, Animals, Backlog, beta-Endorphin/analysis, Bianchi M, Brain, Behavior, And Immunity, Comparative Study, Corticosterone/blood, Corticotropin-Releasing Hormone/antagonists & inhibitors, Corticotropin-Releasing Hormone/blood/pharmacology/physiology, Electroshock/adverse effects, Foot, Helplessness, Journal Article, Killer Cells, Learned, Lymphocyte Activation, Lymphoid Tissue/chemistry, Male, Manfredi B, Natural/immunology, Neuroimmunomodulation/physiology, Panerai AE, Peptide Fragments/pharmacology, Rats, Receptors, Sacerdote P, Spleen/immunology, Sprague-Dawley, Stress/etiology/immunology, Time Factors
On the mathematical modelling of pain
On the dynamics of dying.
Tags: 1997, Animals, Aorta, Aortic Coarctation/pp [Physiopathology], Backlog, Cell Survival/ph [Physiology], Death, Engelberg J, Feedback/ph [Physiology], Female, Heart Arrest/pp [Physiopathology], Hemodynamics/ph [Physiology], Homeostasis/ph [Physiology], Humans, Integrative Physiological And Behavioral Science, Journal Article, Middle Aged, Respiratory Insufficiency/pp [Physiopathology], Thoracic/pp [Physiopathology]
Biological rhythms in pain and in the effects of opioid analgesics
Age-related changes of beta-endorphin and cholecystokinin in human and rat mononuclear cells
Tags: 1991, 80 And Over, Adult, Aged, Aging/blood/immunology, Animals, Backlog, Barcellini W, beta-Endorphin/blood, Breda M, Cholecystokinin/blood, Humans, In Vitro, Interleukin-2/biosynthesis, Journal Article, Leukocytes, Lymphocyte Activation, Male, Meroni PL, Middle Aged, Mononuclear/immunology/metabolism, Panerai AE, Peptides, Rats, Sacerdote P
Gene expression and localization of opioid peptides in immune cells of inflamed tissue: functional role in antinociception
Tags: 1992, Analysis of Variance, Animals, Backlog, beta-Endorphin/genetics/metabolism, Biomarkers of Pain, Biomarkers Reference List, Calcitonin Gene-Related Peptide/analysis/metabolism, Endorphins/analysis/genetics/metabolism, Epplen C, Freund's Adjuvant, Gene Expression/radiation effects, Hassan AH, Herz A, Hindlimb, Inbred Strains, Inflammation/immunology/physiopathology, Journal Article, Lason W, Male, Messenger/genetics/metabolism, Nerve Fibers/physiology/ultrastructure, Neuroscience, Non-U.S. Gov't, Nucleic Acid Hybridization, Oligonucleotide Probes, Pain Measurement, Pain/immunology/physiopathology, Przewlocki R, Rats, Research Support, RNA, Stein C, T-Lymphocytes/immunology/pathology, Whole-Body Irradiation
Pituitary-adrenal function and hypothalamic beta-endorphin release in vitro following food deprivation
Tags: 1993, Adrenal Glands/physiology, Almeida OF, Animals, Backlog, beta-Endorphin/secretion, Blood Glucose/metabolism, Body Weight, Brain Research Bulletin, Corticosterone/blood, Corticotropin-Releasing Hormone/pharmacology, Dexamethasone/pharmacology, Food Deprivation, Hypothalamus/drug effects/secretion, In Vitro, Journal Article, Male, Mitev Y, Non-U.S. Gov't, Organ Size, Patchev V, Pituitary-Adrenal System/physiology, Rats, Research Support, Thymus Gland/physiology, Time Factors, Wistar
Brain and gut neuropeptides in peripheral blood mononuclear cells
Tags: 1993, 80 And Over, Adult, Aged, Aging/metabolism, Animals, Backlog, beta-Endorphin/blood/pharmacology, Brain, Chemotaxis/drug effects, Cholecystokinin/blood/pharmacology, Digestive System, Headache/blood, Humans, Journal Article, Journal Of Physiology, Paris, Lymphocytes/metabolism, Male, Middle Aged, Neuropeptides/blood, Panerai AE, Rats, Sacerdote P, Schizophrenia/blood, Sprague-Dawley, Vasoactive Intestinal Peptide/blood/pharmacology
Bisphosphonates: a review of their pharmacokinetic properties
Tags: 1996, Animals, Backlog, Biological Availability, Blood Proteins/metabolism, Bone, Clodronate, Diphosphonates/pharmacokinetics/urine, Dose-Response Relationship, Drug, Humans, Intestinal Absorption/physiology, Journal Article, Lin JH, Protein Binding, Structure-Activity Relationship, Tissue Distribution/physiology
Quantitative analysis of methionine enkephalin and beta-endorphin in the pituitary by liquid secondary ion mass spectrometry and tandem mass spectrometry
A possible role for saliva as a diagnostic fluid in patients with chronic pain
Tags: 1998, Animals, Arthritis, Backlog, Biomarkers of Pain, Chronic Disease, Eich W, Female, Fibromyalgia/diagnosis/metabolism, Fischer HP, Humans, Journal Article, Male, Neuropeptides/diagnostic use/metabolism, Osteoarthritis/diagnosis/metabolism, Pain/diagnosis/metabolism, Rheumatoid/diagnosis/metabolism, Russell IJ, Saliva, Salivary Proteins/diagnostic use/metabolism, Seminars In Arthritis And Rheumatism, Serotonin/diagnostic use/metabolism, Specimen Handling/methods/standards
Novel opioid peptides endomorphin-1 and endomorphin-2 are present in mammalian immune tissues
Tags: 2000, Adult, Animals, Backlog, Chromatography, Coventry TL, Cross Reactions, De Bree FM, Female, Fulford AJ, Harbuz MS, High Pressure Liquid, Humans, Immune Sera/immunology, Immune System/chemistry, Jessop DS, Journal Article, Journal Of Neuroimmunology, Kaye SJ, Major GN, Male, Middle Aged, Non-U.S. Gov't, Oligopeptides/analysis, Radioimmunoassay/methods, Rats, Research Support, Spleen/chemistry, Thymus Gland/chemistry, Tissue Extracts/chemistry, Wistar
Systemic lidocaine for neuropathic pain relief
Tags: 2000, Administration, Analgesics/administration & dosage/diagnostic use/therapeutic use, Animals, Backlog, Chen LL, Humans, Journal Article, Lidocaine/administration & dosage/diagnostic use/therapeutic use, Mao J, Mexiletine/therapeutic use, Neuralgia/drug therapy/metabolism, Oral, P.H.S., Pain, Research Support, Sodium Channel Blockers, U.S. Gov't
Methionine-enkephalin-and Dynorphin A-release from immune cells and control of inflammatory pain
Tags: 2001, Animals, Antibodies/pharmacology, Backlog, Biomarkers of Pain, Biomarkers Reference List, Cabot PJ, Carter L, Corticotropin-Releasing Hormone/antagonists & inhibitors/pharmacology/therapeutic use, Dose-Response Relationship, Drug, Dynorphins/immunology/secretion, Enkephalin, Humans, Inflammation/drug therapy/immunology/metabolism, Interleukin-2/pharmacology, Journal Article, Lymphocytes/drug effects/immunology/secretion, Male, Methionine/immunology/metabolism, Pain, Pain/drug therapy/immunology/metabolism, Rats, Schafer M, Stein C, Wistar
Efficacy of pharmacological treatments of neuropathic pain: An update and effect related to mechanism of drug action
Tags: 1999, Analgesics/therapeutic use, Animals, Antidepressive Agents, Backlog, Carbamazepine/therapeutic use, Diabetic Neuropathies/complications, Humans, Jensen TS, Journal Article, N-Methylaspartate/antagonists & inhibitors/therapeutic use, Narcotics/therapeutic use, Neuralgia/drug therapy, Non-U.S. Gov't, Pain, Pain/drug therapy/etiology, Polyneuropathies/complications, Randomized Controlled Trials, Research Support, Serotonin Uptake Inhibitors/therapeutic use, Sindrup SH, Tricyclic/therapeutic use
Pain killers of the immune system
Tags: 1997, Animals, Backlog, beta-Endorphin/biosynthesis/physiology, Biomarkers of Pain, Immunohistochemistry, Inflammation/pathology/physiopathology, Journal Article, Messenger/genetics, Nature Medicine, Pain/pathology/physiopathology, Pro-Opiomelanocortin/genetics, Radioimmunoassay, Rats, RNA, Sharp B, T-Lymphocytes/metabolism, Yaksh T
Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue
Tags: 1994, Analysis of Variance, Animals, Antibodies/pharmacology, Backlog, beta-Endorphin/immunology/physiology, Biomarkers of Pain, Carter L, Corticotropin-Releasing Hormone/administration & dosage/pharmacology/therapeutic use, Cyclosporine/pharmacology, Dose-Response Relationship, Drug, Dynorphins/immunology/physiology, Endorphins/immunology/physiology/secretion, Enkephalin, Humans, Inflammation/immunology/physiopathology, Injections, Interleukin-1/administration & dosage/pharmacology/therapeutic use, Journal Article, Leucine/analogs & derivatives/pharmacology, Male, Methionine/immunology/physiology, Naloxone/pharmacology, Pain/immunology/physiopathology/prevention & control, Proceedings Of The National Academy Of Sciences Of The United States Of America, Rats, Recombinant Proteins/pharmacology/therapeutic use, Regression Analysis, Schafer M, Somatostatin/analogs & derivatives/pharmacology, Stein C, Wistar
Opioid peptide-expressing leukocytes: identification, recruitment, and simultaneously increasing inhibition of inflammatory pain
Tags: 2001, Analgesia, Anesthesiology, Animals, Antibodies, Antigens, Backlog, Bauer M, beta-Endorphin/blood, Biomarkers of Pain, Biomarkers Reference List, Brack A, CD45/isolation & purification, Fluorescent Dyes, Hematopoietic Stem Cells/immunology, Immunohistochemistry, Immunomagnetic Separation, Inflammation/chemically induced/metabolism/pathology, Journal Article, Leukocytes/metabolism, Lymphocytes/immunology, Machelska H, Male, Monoclonal/pharmacology, Mousa SA, Opioid Peptides/biosynthesis, Pain Measurement, Pain/physiopathology, Radioimmunoassay, Rats, Rittner HL, Schafer M, Stein C, Wistar