1
40
8
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
2022 Special Edition 3 - Oncology List
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
2022 Special Edition 3 - Oncology List
URL Address
<a href="http://doi.org/10.3389/fonc.2022.1017272" target="_blank" rel="noreferrer noopener"> http://doi.org/10.3389/fonc.2022.1017272</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Compassionate de-escalation of life-sustaining treatments in pediatric oncology: An opportunity for palliative care and intensive care collaboration
Publisher
An entity responsible for making the resource available
Frontiers in Oncology
Date
A point or period of time associated with an event in the lifecycle of the resource
2022
Creator
An entity primarily responsible for making the resource
Cuviello A; Pasli M; Hurley C; Bhatia S; Anghelescu DL; Baker JN
Description
An account of the resource
CONTEXT: Approximately 40%-60% of deaths in the pediatric intensive care unit (PICU) are in the context of de-escalation of life-sustaining treatments (LSTs), including compassionate extubation, withdrawal of vasopressors, or other LSTs. Suffering at the end of life (EOL) is often undertreated and underrecognized. Pain and poor quality of life are common concerns amongst parents and providers at a child's EOL. Integration of palliative care (PC) may decrease suffering and improve symptom management in many clinical situations; however, few studies have described medical management and symptom burden in children with cancer in the pediatric intensive care unit (PICU) undergoing de-escalation of LSTs. METHODS: A retrospective chart review was completed for deceased pediatric oncology patients who experienced compassionate extubation and/or withdrawal of vasopressor support at EOL in the PICU. Demographics, EOL characteristics, and medication use for symptom management were abstracted. Descriptive analyses were applied. RESULTS: Charts of 43 patients treated over a 10-year period were reviewed. Most patients (69.8%) were white males who had undergone hematopoietic stem cell transplantation and experienced compassionate extubation (67.4%) and/or withdrawal of vasopressor support (44.2%). The majority (88.3%) had a physician order for scope of treatment (POST - DNaR) in place an average of 13.9 days before death. PC was consulted for all but one patient; however, in 18.6% of cases, consultations occurred on the day of death. During EOL, many patients received medications to treat or prevent respiratory distress, pain, and agitation/anxiety. Sedative medications were utilized, specifically propofol (14%), dexmedetomidine (12%), or both (44%), often with opioids and benzodiazepines. CONCLUSIONS: Pediatric oncology patients undergoing de-escalation of LSTs experience symptoms of pain, anxiety, and respiratory distress during EOL. Dexmedetomidine and propofol may help prevent and/or relieve suffering during compassionate de-escalation of LSTs. Further efforts to optimize institutional policies, education, and collaborations between pediatric intensivists and PC teams are needed.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.3389/fonc.2022.1017272" target="_blank" rel="noreferrer noopener">10.3389/fonc.2022.1017272</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2022
2022 Special Edition 3 - Oncology List
Anghelescu DL
Baker JN
Bhatia S
Cuviello A
Dexmedetomidine
End Of Life
Frontiers in Oncology
Hurley C
Palliative Care
Palliative sedation
Pasli M
Pediatric Oncology
Propofol
Symptom Management
Therapy
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
January 2023 List
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
January List 2023
URL Address
<a href="http://doi.org/10.1177/10499091221138298" target="_blank" rel="noreferrer noopener"> http://doi.org/10.1177/10499091221138298</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Palliative Sedation Therapy Practice Comparison – A Survey of Pediatric Palliative Care and Pain Management Specialists
Publisher
An entity responsible for making the resource available
American Journal of Hospice and Palliative Medicine®
Date
A point or period of time associated with an event in the lifecycle of the resource
2022
Subject
The topic of the resource
Dexmedetomidine; End of Life; Pain Management; Palliative Care; Palliative Sedation Therapy; Propofol; Symptom Management
Creator
An entity primarily responsible for making the resource
Cuviello A; Ang N; Morgan K; Baker JN; Anghelescu DL
Description
An account of the resource
Context: Palliative sedation therapy (PST) can relieve suffering at end-of-life (EOL) in children with intolerable and refractory symptoms. However, updated and consistent guidance on PST practices are imperative. Objectives: We investigate current variations in clinical practice and PST implementation among pediatric palliative care (PPC) and pain management (PM) specialists. Methods: We distributed an IRB-exempt electronic anonymous survey via email through the Society of Pediatric Pain Medicine, and the American Academy of Hospice and Palliative Medicine. Survey responses were collated and descriptively reported. Results: Of 83 survey responses, the majority (75%) represented large academic children’s hospitals. The distribution between PPC and pediatric pain management specialists’ responses was 60% and 40%, respectively. Most respondents reported having designated pain management and/or palliative care teams (70% and 90%, respectively). Approximately half (48%) reported following an institutional PST protocol, most not requiring formal ethics consult (69%). Only 54% of respondents noted that the Do Not Resuscitate (DNR) order was required prior to PST initiation. PST was primarily utilized for children with oncologic diagnoses (76%). The primary and secondary medications of choice for PST implementation were reported to be opioids (39%) and benzodiazepines (36%) by pain management specialists, and benzodiazepines (52%) and barbiturates (28%) by palliative care specialists. Conclusions: Our study highlights the variability in the practice and implementation of PST. Further educational efforts are key for establishing PST practices and efficient protocol development.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1177/10499091221138298" target="_blank" rel="noreferrer noopener">10.1177/10499091221138298</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Palliative Care
2022
American Journal of Hospice and Palliative Medicine®
Ang N
Anghelescu DL
Baker JN
Cuviello A
Dexmedetomidine
End Of Life
January List 2023
Morgan K
Pain Management
Palliative Sedation Therapy
Propofol
Symptom Management
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
January 2023 List
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
January List 2023
URL Address
<a href="http://doi.org/10.3390/children9121887" target="_blank" rel="noreferrer noopener"> http://doi.org/10.3390/children9121887</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Palliative Sedation Therapy in Pediatrics: An Algorithm and Clinical Practice Update
Publisher
An entity responsible for making the resource available
Children
Date
A point or period of time associated with an event in the lifecycle of the resource
2022
Subject
The topic of the resource
Palliative; Sedation
Creator
An entity primarily responsible for making the resource
Cuviello A; Johnson LM; Morgan K; Anghelescu DL; Baker JN
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.3390/children9121887" target="_blank" rel="noreferrer noopener">10.3390/children9121887</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2022
Anghelescu DL
Baker JN
Children
Cuviello A
January List 2023
Johnson LM
Morgan K
Palliative
Sedation
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/j.jpainsymman.2015.03.008" target="_blank" rel="noreferrer">http://doi.org/10.1016/j.jpainsymman.2015.03.008</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Patterns of End-of-Life Care in Children with Advanced Solid Tumor Malignancies Enrolled on a Palliative Care Service
Publisher
An entity responsible for making the resource available
Journal Of Pain And Symptom Management
Date
A point or period of time associated with an event in the lifecycle of the resource
2015
Creator
An entity primarily responsible for making the resource
Vern-Gross Tamara Z; Lam CG; Graff Z; Singhal S; Levine DR; Gibson D; Sykes AD; Anghelescu DL; Yuan Y; Baker JN
Description
An account of the resource
CONTEXT: Pediatric patients with solid tumors can have a significant symptom burden that impacts quality of life (QoL) and end-of-life care needs. OBJECTIVES: We evaluated outcomes and symptoms in children with solid tumors and compared patterns of end-of-life care after implementation of a dedicated institutional pediatric palliative care (PC) service. METHODS: We performed a retrospective cohort study of children with solid tumors treated at St. Jude Children's Research Hospital, before and after implementation of the institutional QoL/PC service in January 2007. Patients who died between July 2001 and February 2005 (historical cohort; n = 134) were compared with those who died between January 2007 and January 2012 (QoL/PC cohort; n = 57). RESULTS: Median time to first QoL/PC consultation was 17.2 months (range 9-33). At consultation, 60% of children were not receiving or discontinued cancer-directed therapy. Within the QoL/PC cohort, 54 patients had documented symptoms, 94% required intervention for ≥3 symptoms, and 76% received intervention for ≥5 symptoms. Eighty-three percent achieved their preferred place of death. Compared with the historical cohort, the QoL/PC cohort had more end-of-life discussions per patient (median 12 vs. 3; P < 0.001), earlier end-of-life discussions, with longer times before do-not-resuscitate orders (median 195 vs. 2 days; P < 0.001), and greater hospice enrollment (71% vs. 46%, P = 0.002). CONCLUSION: Although children with solid tumor malignancies may have significant symptom burden toward the end of life, positive changes were documented in communication and in places of care and death after implementation of a pediatric PC service.
2015-04
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.jpainsymman.2015.03.008" target="_blank" rel="noreferrer">10.1016/j.jpainsymman.2015.03.008</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2015
Anghelescu DL
Backlog
Baker JN
Gibson D
Graff Z
Journal Article
Journal of Pain and Symptom Management
Lam CG
Levine DR
Singhal S
Sykes AD
Vern-Gross Tamara Z
Yuan Y
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1002/pbc.25493" target="_blank" rel="noreferrer">http://doi.org/10.1002/pbc.25493</a>
<a href="http://dx.doi.org/10.1002/pbc.25493" target="_blank" rel="noreferrer">http://dx.doi.org/10.1002/pbc.25493</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Patient-controlled analgesia at the end of life at a pediatric oncology institution
Publisher
An entity responsible for making the resource available
Pediatric Blood & Cancer
Date
A point or period of time associated with an event in the lifecycle of the resource
2015
Subject
The topic of the resource
opioid analgesics; pain control; Pediatric pain control
Creator
An entity primarily responsible for making the resource
Anghelescu DL; Snaman JM; Trujillo L; Sykes AD; Yuan Y; Baker JN
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/pbc.25493" target="_blank" rel="noreferrer">10.1002/pbc.25493</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
2015-07
2015
Anghelescu DL
Backlog
Baker JN
Journal Article
opioid analgesics
Pain Control
Pediatric Blood & Cancer
Pediatric Pain Control
Snaman JM
Sykes AD
Trujillo L
Yuan Y
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/j.jpainsymman.2005.05.007" target="_blank" rel="noreferrer">http://doi.org/10.1016/j.jpainsymman.2005.05.007</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Ketamine use for reduction of opioid tolerance in a 5-year-old girl with end-stage abdominal neuroblastoma
Publisher
An entity responsible for making the resource available
Journal Of Pain And Symptom Management
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
Subject
The topic of the resource
U.S. Gov't; PedPal Lit; Extramural Research Support; N.I.H.; Non-U.S. Gov't Research Support; Abdominal Neoplasms/complications Abdominal Pain/etiology/prevention & control Analgesics; Dissociative/administration & dosage Child; Opioid/administration & dosage Anesthetics; P.H.S. Terminal Care/methods Treatment Outcome; Preschool Drug Administration Schedule Drug Combinations Drug Tolerance Female Humans Ketamine/administration & dosage Neuroblastoma/complications Palliative Care/methods Research Support
Creator
An entity primarily responsible for making the resource
Anghelescu DL; Oakes L
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.jpainsymman.2005.05.007" target="_blank" rel="noreferrer">10.1016/j.jpainsymman.2005.05.007</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
2005
2005
Abdominal Neoplasms/complications Abdominal Pain/etiology/prevention & control Analgesics
Anghelescu DL
Backlog
Dissociative/administration & dosage Child
Extramural Research Support
Journal Article
Journal of Pain and Symptom Management
N.I.H.
Non-U.S. Gov't Research Support
Oakes L
Opioid/administration & dosage Anesthetics
P.H.S. Terminal Care/methods Treatment Outcome
PedPal Lit
Preschool Drug Administration Schedule Drug Combinations Drug Tolerance Female Humans Ketamine/administration & dosage Neuroblastoma/complications Palliative Care/methods Research Support
U.S. Gov't
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16487900" target="_blank" rel="noreferrer">http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16487900</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Palliative care and pediatrics
Publisher
An entity responsible for making the resource available
Anesthesiology Clinics of North America
Date
A point or period of time associated with an event in the lifecycle of the resource
2006
Subject
The topic of the resource
PedPal Lit
Creator
An entity primarily responsible for making the resource
Anghelescu DL; Oakes L; Hinds PS
Description
An account of the resource
This article reviews the unique challenges of pediatric palliative medicine. These challenges originate from the specific epidemiology of pediatric diseases for which palliative care is indicated and the necessity to provide child-focused, family-oriented, relationship-centered medical care. The emphasis of the ultimate aims of pediatric palliative care is to care for the body, mind, and spirit, to enhance quality of life, and to minimize suffering.
2006
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2006
Anesthesiology Clinics of North America
Anghelescu DL
Backlog
Hinds PS
Journal Article
Oakes L
PedPal Lit
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1089/jpm.2011.0500" target="_blank" rel="noreferrer">http://doi.org/10.1089/jpm.2011.0500</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pediatric palliative sedation therapy with propofol: recommendations based on experience in children with terminal cancer
Publisher
An entity responsible for making the resource available
Journal Of Palliative Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
Subject
The topic of the resource
Intervention; Interventions; KPM Briefings
Creator
An entity primarily responsible for making the resource
Anghelescu DL; Hamilton H; Faughnan LG; Johnson LM; Baker JN
Description
An account of the resource
Abstract Background: The use of propofol for palliative sedation of children is not well documented. Objective: Here we describe our experience with the use of propofol palliative sedation therapy (PST) to alleviate intractable end-of-life suffering in three pediatric oncology patients, and propose an algorithm for the selection of such candidates for PST. Patients and Methods: We identified inpatients who had received propofol PST within 20 days of death at our institution between 2003 and 2010. Their medical records were reviewed for indicators of pain, suffering, and sedation from 48 hours before PST to the time of death. We also tabulated consumption of opioids and other symptom management medications, pain scores, and adverse events of propofol, and reviewed clinical notes for descriptors of suffering and/or palliation. Results: Three of 192 (1.6%) inpatients (aged 6-15 years) received propofol PST at the end of life. Consumption of opioids and other supportive medications decreased during PST in two cases. In the third case, pain scores remained high and sedation was the only effective comfort measure. Clinical notes suggested improved comfort and rest in all patients. Propofol infusions were continued until the time of death. Conclusions: Our experience demonstrates that propofol PST is a useful palliative option for pediatric patients experiencing intractable suffering at the end of life. We describe an algorithm that can be used to identify such children who are candidates for PST.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1089/jpm.2011.0500" target="_blank" rel="noreferrer">10.1089/jpm.2011.0500</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2012
Anghelescu DL
Backlog
Baker JN
Faughnan LG
Hamilton H
Intervention
Interventions
Johnson LM
Journal Article
Journal of Palliative Medicine
KPM Briefings