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Dublin Core
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Title
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Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
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URL Address
<a href="http://doi.org/10.1007/s11325-010-0432-6" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s11325-010-0432-6</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Respiratory events and obstructive sleep apnea in children with achondroplasia: investigation and treatment outcomes
Publisher
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Sleep and Breathing
Date
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2011
Subject
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Cross-Sectional Studies; Age Factors; Male; Treatment Outcome; Comorbidity; Child; Humans; Adolescent; Cohort Studies; Female; Child Preschool; Infant; Polysomnography; Body Mass Index; Achondroplasia/di [Diagnosis]; Achondroplasia/th [Therapy]; Sleep Apnea Central/di [Diagnosis]; Sleep Apnea Central/th [Therapy]; Sleep Apnea Obstructive/di [Diagnosis]; Sleep Apnea Obstructive/th [Therapy]; Achondroplasia/ep [Epidemiology]; Airway Obstruction/di [Diagnosis]; Airway Obstruction/ep [Epidemiology]; Airway Obstruction/th [Therapy]; Sleep Apnea Central/ep [Epidemiology]; Sleep Apnea Obstructive/ep [Epidemiology]; breathing difficulties; achondroplasia; trajectory; characteristics; obstructive sleep apnea
Creator
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Afsharpaiman S; Sillence D O; Sheikhvatan M; Ault J E; Waters K
Description
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PURPOSE: We report aspects of sleep-disordered breathing in a cohort of achondroplastic children who attended our hospital. METHODS: A retrospective chart review was conducted for a 15-year period to further evaluate the diagnosis and treatment of sleep-disordered breathing in children with achondroplasia. RESULTS: A review of the medical records was undertaken for 46 children (63%, mean age 3.9 years) with achondroplasia that had overnight polysomnography. Among them, 25 (54.3%) had obstructive sleep apnea (OSA). For 19 out of 46 patients (follow-up rate, 41.3%) with a mean follow-up of 31.3 months (range, 3 month to 11 years), 13 had undergone adenotonsillectomy, while nine were treated with continuous positive airway pressure. CONCLUSIONS: Prospective evaluation of our clinic population confirms a high incidence of SDB in achondroplastic children. OSA has been linked to raise intracranial pressure as well as neurocognitive deficits in children and we hypothesize that associations between neurological and respiratory abnormalities in this disorder are a consequence of the early onset of associated respiratory, rather than the neurological complications.
Identifier
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<a href="http://doi.org/10.1007/s11325-010-0432-6" target="_blank" rel="noreferrer noopener">10.1007/s11325-010-0432-6</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2011
achondroplasia
Achondroplasia/di [Diagnosis]
Achondroplasia/ep [Epidemiology]
Achondroplasia/th [Therapy]
Adolescent
Afsharpaiman S
Age Factors
Airway Obstruction/di [Diagnosis]
Airway Obstruction/ep [Epidemiology]
Airway Obstruction/th [Therapy]
Ault J E
Body Mass Index
breathing difficulties
characteristics
Child
Child Preschool
Cohort Studies
Comorbidity
Cross-sectional Studies
Female
Humans
Infant
Male
obstructive sleep apnea
Polysomnography
Sheikhvatan M
Sillence D O
Sleep and Breathing
Sleep Apnea Central/di [Diagnosis]
Sleep Apnea Central/ep [Epidemiology]
Sleep Apnea Central/th [Therapy]
Sleep Apnea Obstructive/di [Diagnosis]
Sleep Apnea Obstructive/ep [Epidemiology]
Sleep Apnea Obstructive/th [Therapy]
Trajectory
Treatment Outcome
Waters K